Job Description

Research Scientist - Cancer Immunotherapy for Pediatric Cancer Nationwide Children's Hospital provided pay range: this range is provided by Nationwide Children's Hospital. Your actual pay will be based on your skills and experience — talk with your recruiter to learn more. Base pay range: $75,000.00/yr - $90,000.00/yr. Dr. Dean Lee's Lab Dr. Lee's research program focuses on advancing translational NK cell therapies for pediatric cancers. Our work spans in vitro function (cytotoxicity, cytokines, avidity), immunophenotyping (mass cytometry), genomics/epigenomics (RNAseq, ATACseq, ChIPseq, methylation), and in vivo xenograft, PDX, and canine models. Current focuses: inhibitory TME (hypoxia, TGFβ, kynurenine), NK checkpoints (TIGIT, TIM3, VISTA), activation (ITAM/ITIM, CAR design, cytokines), and Cas9/AAV engineering. We also perform correlative studies of early-phase NK therapy trials. Disease targets include AML/MDS, brain tumors, pediatric sarcomas, and select adult malignancies. The lab has broad federal, foundation, industry, and institutional sources of support. Summary Conducts independent research, designs experiments, analyzes data, and presents findings under the mentorship of a principal investigator. Assists with training and mentorship. Essential Functions Designs experiments, develops protocols, and conducts research with faculty PI under minimal guidance. Serves as a mentor and training aide to new or junior staff. Trains and supervises technical support staff in performing specific techniques essential to carrying out the research program. Records and analyzes data generated by the research study. Assists in the development of hypotheses for further investigation from the results of the studies performed. Prepares scientific and technical papers for publication in peer-reviewed journals. Presents findings at local and national research forums. Collaborates with other ongoing research efforts either at NCH or at The Ohio State University. Works toward research independence, preparing to submit proposals to and obtain funding from external granting agencies. Education PhD or equivalent degree in relevant field of science, required. Skills Effective interpersonal skills required in interactions with scientists, physicians, and laboratory colleagues. Excellent laboratory technical skills. Skills in qualitative and quantitative research methods. Ability to proactively manage and drive projects. Seniority Level Mid-Senior level Employment Type Full-time Job Function Science, Research, and Health Care Provider Industries Hospitals and Health Care, Research Services, and Higher Education Benefits Medical insurance Vision insurance 401(k) Pension plan Paid maternity leave Paid paternity leave Disability insurance Tuition assistance Location: Columbus, OH #J-18808-Ljbffr Nationwide Children's Hospital

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